Category: Research summaries

Repeated Administration of 2-Hydroxypropyl-β-Cyclodextrin (HPβCD) Attenuates the Chronic Inflammatory Response to Experimental Stroke

Repeated Administration of 2-Hydroxypropyl-β-Cyclodextrin (HPβCD) Attenuates the Chronic Inflammatory Response to Experimental Stroke

Stoke IMPaCT researchers wanted to investigate what happens when too many lipids, fatty substances that make up different structures of the brain’s cells, are released from dying cells. The scientists in this study hypothesised that build up of lipids and the formation of foam cells may make the inflammatory response worse and lead to the production of toxic molecules, which could contribute to cognitive decline in patients.